Methane

Methane

SCHEMBL9150719

C.O=C(O)CC(C(=O)O)S(=O)(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.38
FOLH1 Q04609 2/20 0.34
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
SRC P12931 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698543 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
Hydrogen Peroxide SCHEMBL28115963 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL42084 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL987086 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10698540 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL9777404 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10698553 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL11360544 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL11346775 0.95 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL10777605 0.95 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083696-B2 Dispersion anaesthetic device UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2021-08-10 US claimed
EP-3326677-A1 INHALABLE MICROEMULSION COMPRISING ANAESTHETIC University College Cardiff Consultants Limited (GB) 2018-05-30 EP claimed
US-20180085325-A1 DISPERSION ANAESTHETIC DEVICE UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2018-03-29 US claimed
US-9827394-B2 Dispersion anaesthetic device UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2017-11-28 US claimed
US-20140216456-A1 DISPERSION ANAESTHETIC DEVICE UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2014-08-07 US claimed
EP-2758114-A2 INHALABLE MICROEMULSION COMPRISING ANAESTHETIC University College Cardiff Consultants, Ltd. (GB) 2014-07-30 EP claimed
WO-2013041850-A2 DISPERSION ANAESTHETIC DEVICE UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-03-28 WO claimed
US-5393461-A For use in cosmetics, paints, drugs,inks; mixing powder with anionic, cationic, amphoteric, nonionic surfactants, oils, solvents, wetting agents and water, emulsification RTD CORPORATION (US) 1995-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11083696-B2 Dispersion anaesthetic device ADRA1D, CHRM5, ADRA2C TDP1 2595/4885SMN1; SMN2 687/4885SLC22A6 2575/4885
US-20180085325-A1 DISPERSION ANAESTHETIC DEVICE ADRA1D, CHRM5, ADRA2C TDP1 2595/4885SMN1; SMN2 687/4885SLC22A6 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.