Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578364 | 0.68 | MAOA (0.36) | MAOAGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL24113001 | 0.68 | MAOA (0.46) | MAOAGAAGRM2SMN1; SMN2CYP1A2 | |
| SCHEMBL4303560 | 0.68 | NOTUM (0.38) | GAAKDM4EALDH1A1TDP1NOTUM | |
| SCHEMBL27724536 | 0.68 | MAOA (0.46) | MAOAGAAGRM2SMN1; SMN2CYP1A2 | |
| SCHEMBL3534265 | 0.68 | MAOA (0.36) | MAOAGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL4669702 | 0.67 | GRM2 (0.54) | GRM2SMN1; SMN2FADS1 | |
| SCHEMBL4670666 | 0.67 | GRM2 (0.54) | GRM2SMN1; SMN2FADS1 | |
| SCHEMBL2322579 | 0.67 | GRM2 (0.54) | GRM2SMN1; SMN2FADS1 | |
| SCHEMBL24794863 | 0.67 | GRM5 (0.54) | MAOAGRM2MEN1KMT2A | |
| SCHEMBL10797528 | 0.66 | MEN1 (0.44) | GAAKDM4EALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254578-A1 | Antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |