Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22241342 | 0.86 | MEN1 (0.42) | MEN1KMT2AGAAMAPTRAB9A | |
| SCHEMBL6987111 | 0.80 | NOTUM (0.50) | NOTUMALOX5 | |
| SCHEMBL15775108 | 0.75 | MEN1 (0.37) | MEN1KMT2AGAAALOX5G6PD | |
| SCHEMBL15775916 | 0.74 | MEN1 (0.39) | MEN1KMT2AGAAALOX5G6PD | |
| SCHEMBL22560034 | 0.74 | MEN1 (0.42) | MEN1KMT2AGAAALOX5G6PD | |
| SCHEMBL31663152 | 0.74 | GAA (0.44) | MEN1KMT2AHPGDGAAALOX5 | |
| SCHEMBL2234874 | 0.74 | GAA (0.44) | MEN1KMT2AHPGDGAAALOX5 | |
| SCHEMBL4553559 | 0.73 | QPCT (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6228521 | 0.72 | PARP3 (0.35) | KMT2AGAAALDH1A1RAB9AKDM4E | |
| SCHEMBL289664 | 0.71 | P2RX7 (0.51) | NOTUMMEN1KMT2AITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |