Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13454073 | 0.92 | MAPT (0.57) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10699304 | 0.85 | ESR2 (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL3035436 | 0.82 | ALDH1A1 (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10699999 | 0.82 | ESR2 (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL25375645 | 0.82 | MAPT (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9308995 | 0.80 | ESR2 (0.58) | KMT2AMEN1NPC1RAB9ATNKS2 | |
| SCHEMBL427824 | 0.79 | HTR2C (0.53) | MAPTGAA | |
| SCHEMBL25374925 | 0.78 | MAPT (0.42) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL628247 | 0.78 | TSHR (0.46) | MAPTTNKS2TNKSPARP3TSHR | |
| SCHEMBL9706513 | 0.76 | TSHR (0.56) | KMT2AMEN1MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259977-A2 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-16 | — | — | EP | disclosed |