Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399652 | 0.98 | MAOB (0.68) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL13971316 | 0.95 | MAOB (0.65) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL30324526 | 0.91 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL29569802 | 0.91 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL9719373 | 0.91 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL3482569 | 0.91 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| Diphenylmethane SCHEMBL17414841 | 0.91 | MAOB (0.64) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL49433 | 0.91 | MAOB (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL30583096 | 0.91 | MAOB (0.62) | MAOBMAOACALM1CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL9007433 | 0.89 | CYP19A1 (0.67) | MAOBMAOACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257011-A2 | Permeation modified asymmetric gas separation membranes having graded density skins | PERMEA, Inc. (US) | 1988-02-24 | — | — | EP | disclosed |