Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.68 |
| ▸ | MAOA | P21397 | 4/20 | 0.68 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13971316 | 0.98 | MAOB (0.65) | MAOBMAOACALM1CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL10698619 | 0.98 | MAOB (0.65) | MAOBMAOACALM1CA1CA2 | |
| Diphenylmethane SCHEMBL17414841 | 0.93 | MAOB (0.64) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL9719373 | 0.93 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL29569802 | 0.93 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL30324526 | 0.93 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL3482569 | 0.93 | CA1 (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL49433 | 0.93 | MAOB (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL30583096 | 0.93 | MAOB (0.62) | MAOBMAOACALM1CA1CA2 | |
| SCHEMBL9719335 | 0.90 | MAOB (0.60) | MAOBMAOACALM1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184603-A | Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof | 天津科技大学 | 2024-06-14 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| CN-104419416-B | Liquid composition containing phosphorescent light-emitting materials | 住友化学株式会社 | 2017-03-29 | — | — | CN | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050004367-A1 | Sulfonamide derivatives | DU DANIEL Y (US) | 2005-01-06 | — | — | US | claimed |
| EP-4663636-A2 | TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250270171-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-28 | — | — | US | disclosed |
| US-20250257040-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-14 | — | — | US | disclosed |
| EP-4180424-B1 | SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2025-06-25 | — | — | EP | disclosed |
| CN-119661386-A | Synthesis method and compound of 3-amino-5- (4-methoxybenzyl) -2-nitrobenzoic acid methyl ester | 上海毕得医药科技股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-12162838-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-4279637-A | Herbicidal N-substituted 4-imidazolin-2-ones | VELSICOL CHEMICAL CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |
| US-4189443-A | BOILING AROMATIC AMINE UNDER REFLUX, CONDENSATION POLYMERIZATION WUTH FORMALDEHYDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4089901-A | HEATING IN WATER WITH MONOARYLAMINE, SOLID ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4083870-A | Process for converting polyaminopolyaryl-methanes into diaminodiarylmethanes | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3972926-A | MICROBIOCIDE | RIKER LABORATORIES, INC. (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004367-A1 | Sulfonamide derivatives | AR, SULT2A1, SHBG | MAOB 2371/4885MAOA 1548/4885CALM1 2913/4885 |
| US-20250270171-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | MAOB 588/4885MAOA 598/4885CALM1 4350/4885 |
| US-20250257040-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | MAOB 588/4885MAOA 598/4885CALM1 4350/4885 |
| US-12162838-B2 | Human plasma kallikrein inhibitors | KLKB1, KLK5, KLK1 | MAOB 588/4885MAOA 598/4885CALM1 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.