Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898489 | 0.88 | LMNA (0.54) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL30023814 | 0.88 | LMNA (0.54) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL10584542 | 0.86 | LMNA (0.57) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL29015206 | 0.86 | USP2 (0.74) | LMNANPC1L1USP2 | |
| SCHEMBL863638 | 0.86 | USP2 (0.74) | LMNANPC1L1USP2 | |
| SCHEMBL14924215 | 0.86 | USP2 (0.74) | LMNANPC1L1USP2 | |
| SCHEMBL29289385 | 0.85 | GPBAR1 (0.69) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL29465677 | 0.84 | LMNA (0.52) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL1517837 | 0.84 | LMNA (0.56) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL27730341 | 0.84 | LMNA (0.56) | LMNANPC1L1USP2GPBAR1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282984-A1 | 23-Phenylsteroids | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-09-21 | — | — | EP | disclosed |