SCHEMBL10698659

SCHEMBL10698659

O[SiH2]CC=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.52
IDO1 P14902 2/20 0.47
MAOB P27338 2/20 0.44
HTR2A P28223 3/20 0.44
GRIK1 P39086 2/20 0.42
GRIK2 Q13002 2/20 0.42
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21328507 0.81 IDO1 (0.50) PAMIDO1MAOBHTR2A
SCHEMBL886949 0.78 IDO1 (0.48) PAMIDO1MAOBHTR2AHDAC3
SCHEMBL17491567 0.77 IDO1 (0.47) PAMIDO1MAOBHTR2A
SCHEMBL9256819 0.77 IDO1 (0.47) PAMIDO1MAOBHTR2A
SCHEMBL4863423 0.75 IDO1 (0.58) PAMIDO1MAOBHTR2AALDH1A1
SCHEMBL9777486 0.75 IDO1 (0.58) PAMIDO1MAOBHTR2AALDH1A1
Cinnamic Alcohol SCHEMBL39219 0.73 PAM (0.58) PAMIDO1MAOBHTR2AHDAC3
Cinnamic Alcohol SCHEMBL4175503 0.73 PAM (0.58) PAMIDO1MAOBHTR2AHDAC3
Cinnamic Alcohol SCHEMBL39220 0.73 PAM (0.58) PAMIDO1MAOBHTR2AHDAC3
Cinnamic Alcohol SCHEMBL28583889 0.73 PAM (0.58) PAMIDO1MAOBHTR2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1314086-C Process for wafer level treatment to reduce stiction and passivate micromachined surfaces and compound used therefor ANALAG DEVICES INC (US) 2007-05-02 CN claimed
CN-87105866-A PESTICIDAL COMPOSITION 1988-05-04 CN disclosed
EP-0258055-A2 A new pesticidal composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-03-02 EP disclosed
EP-0237271-A2 A sesquilignan derivative Nippon Kayaku Kabushiki Kaisha (JP) 1987-09-16 EP disclosed