SCHEMBL9256819

SCHEMBL9256819

Br[SiH2]CC=Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
PAM P19021 1/20 0.47
MAOB P27338 2/20 0.44
HTR2A P28223 3/20 0.44
SIGMAR1 Q99720 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NFE2L2 Q16236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21328507 0.81 IDO1 (0.50) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL17491567 0.77 IDO1 (0.47) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL10698659 0.77 PAM (0.52) IDO1PAMMAOBHTR2A
SCHEMBL9777486 0.75 IDO1 (0.58) IDO1PAMMAOBHTR2ANPC1
SCHEMBL4863423 0.75 IDO1 (0.58) IDO1PAMMAOBHTR2ANPC1
SCHEMBL250822 0.73 IDO1 (0.52) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL1919743 0.73 IDO1 (0.52) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL625625 0.73 IDO1 (0.52) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL7568412 0.72 IDO1 (0.56) IDO1PAMMAOBHTR2ASIGMAR1
SCHEMBL7939387 0.72 IDO1 (0.56) IDO1PAMMAOBHTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446895-B1 Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it KAO CORP (JP) 1995-08-02 EP disclosed
US-5352554-A Organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it KAO CORPORATION (JP) 1994-10-04 US disclosed
US-5290963-A Silane containing triarylamines, prepared from Grignard reagents, electrography KAO CORPORATION (JP) 1994-03-01 US disclosed
US-5187310-A Sensitivity, durability KAO CORPORATION (JP) 1993-02-16 US disclosed
EP-0457212-A1 Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it Kao Corporation (JP) 1991-11-21 EP disclosed
EP-0446895-A1 Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it Kao Corporation (JP) 1991-09-18 EP disclosed