Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698763 | 0.86 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL9733582 | 0.85 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL9734563 | 0.83 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1LMNAGRM2PPARG | |
| SCHEMBL9734313 | 0.83 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1LMNAGRM2PPARG | |
| SCHEMBL10680378 | 0.83 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL9734317 | 0.83 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10693436 | 0.81 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| Tomelukast SCHEMBL3944 | 0.80 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10891172 | 0.80 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1LMNAGRM2PPARG | |
| SCHEMBL10687786 | 0.79 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252639-A1 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1988-01-13 | — | — | EP | disclosed |