SCHEMBL10698769

SCHEMBL10698769

Cc1ccnn1-c1ccc(N)cc1S(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
POLB P06746 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
GAA P10253 2/20 0.42
RECQL P46063 2/20 0.42
CASP6 P55212 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ELAVL1 Q15717 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.39
NSD2 O96028 1/20 0.38
APEX1 P27695 1/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10393847 0.71 MAPT (0.47) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL11584676 0.70 ALDH1A1 (0.43) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL29648925 0.69 ALDH1A1 (0.54) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL151537 0.69 ALDH1A1 (0.54) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL10706527 0.68 MAPT (0.56) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL10701733 0.68 MAPT (0.56) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL11016468 0.68 MAPT (0.58) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL29045366 0.68 ALDH1A1 (0.53) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL8394451 0.68 ALDH1A1 (0.53) ALDH1A1MAPTPOLBTDP1KDM4E
SCHEMBL7840819 0.68 MAPT (0.44) ALDH1A1MAPTPOLBTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4782140-A Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge CIBA-GIEGY CORPORATION (US) 1988-11-01 US disclosed