Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | RECQL | P46063 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | NT5E | P21589 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648925 | 0.98 | ALDH1A1 (0.54) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL151537 | 0.98 | ALDH1A1 (0.54) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL29045366 | 0.96 | ALDH1A1 (0.53) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL4890522 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| Acetoacetic Acid SCHEMBL11035462 | 0.82 | ALDH1A1 (0.46) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL9312016 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL158650 | 0.82 | L3MBTL1 (0.68) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL636186 | 0.81 | L3MBTL1 (0.55) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL9768796 | 0.80 | CASP1 (0.57) | ALDH1A1RECQLTDP1L3MBTL1POLB | |
| SCHEMBL10383132 | 0.80 | LMNA (0.53) | ALDH1A1L3MBTL1POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611372-B1 | PHOTOSENSITIZERS | JOHNSON MATTHEY PLC (GB) | 1999-05-26 | — | — | EP | disclosed |