Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808459 | 0.87 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL1245169 | 0.85 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL1244585 | 0.81 | HSP90AA1 (0.38) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL10697033 | 0.81 | MEN1 (0.39) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL28386966 | 0.79 | KDM4E (0.39) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL1245481 | 0.79 | MEN1 (0.36) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL11705589 | 0.78 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL10956529 | 0.76 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL294290 | 0.76 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL2334220 | 0.76 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273864-A2 | Diphenylmethanes | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |