Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808459 | 0.82 | KDM4E (0.42) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL10698817 | 0.81 | KDM4E (0.41) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL11310170 | 0.80 | KDM4E (0.36) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL11318649 | 0.79 | KDM4E (0.37) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL11023683 | 0.79 | CYP1A2 (0.32) | MEN1KMT2AKDM4EMAPTPTGDR2 | |
| SCHEMBL11478194 | 0.78 | S1PR1 (0.41) | MEN1KMT2AKDM4EMAPTPTGDR2 | |
| SCHEMBL28386966 | 0.75 | KDM4E (0.39) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL11472304 | 0.75 | EPHX2 (0.40) | MEN1KMT2AKDM4EMAPTPTGDR2 | |
| SCHEMBL3188063 | 0.75 | NUDT1 (0.36) | MEN1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL29636489 | 0.75 | NUDT1 (0.36) | MEN1KMT2AKDM4EMAPTNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280240-A2 | Cephalosporin derivatives, process for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-08-31 | — | — | EP | disclosed |
| EP-0273864-A2 | Diphenylmethanes | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |