Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826528 | 0.87 | MME (0.52) | MME | |
| SCHEMBL10826470 | 0.85 | ACE (0.49) | MME | |
| SCHEMBL10826319 | 0.84 | CYP3A4 (0.49) | MME | |
| SCHEMBL10826350 | 0.82 | MME (0.49) | MME | |
| SCHEMBL9444948 | 0.81 | MME (0.41) | MME | |
| SCHEMBL9727512 | 0.80 | MME (0.47) | MME | |
| SCHEMBL5598606 | 0.80 | MME (0.46) | MME | |
| SCHEMBL10826321 | 0.80 | MMP1 (0.49) | MME | |
| SCHEMBL7307690 | 0.80 | MME (0.49) | MME | |
| SCHEMBL5598613 | 0.80 | MME (0.46) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278158-A2 | Renin inhibitors containing phenylalanyl-histidine replacements | MERCK & CO. INC. (US) | 1988-08-17 | — | — | EP | claimed |
| EP-0278158-A2 | Renin inhibitors containing phenylalanyl-histidine replacements | MERCK & CO. INC. (US) | 1988-08-17 | — | — | EP | disclosed |