Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826528 | 0.82 | MME (0.52) | MME | |
| SCHEMBL7312789 | 0.82 | MME (0.46) | MMEALDH1A1TSHR | |
| SCHEMBL7310410 | 0.82 | MME (0.46) | MMEALDH1A1TSHR | |
| SCHEMBL7310400 | 0.82 | MME (0.46) | MMEALDH1A1TSHR | |
| SCHEMBL7312761 | 0.82 | MME (0.46) | MMEALDH1A1TSHR | |
| SCHEMBL10698837 | 0.81 | MME (0.46) | MME | |
| SCHEMBL7268403 | 0.79 | MME (0.50) | MME | |
| SCHEMBL10826470 | 0.78 | ACE (0.49) | MME | |
| SCHEMBL10826350 | 0.77 | MME (0.49) | MME | |
| SCHEMBL9444982 | 0.76 | CYP1A2 (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204357-A | RENIN-INHIBITING AMINO ACID DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |