Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696497 | 0.85 | PTPN1 (0.35) | PTGER2PPARGPPARASLC6A3DHFR | |
| SCHEMBL19291655 | 0.82 | DHFR (0.43) | BCHEDHFR | |
| SCHEMBL2205030 | 0.81 | DHFR (0.45) | DHFR | |
| SCHEMBL13779680 | 0.81 | DHFR (0.44) | BCHESLC6A3DHFR | |
| SCHEMBL12432781 | 0.79 | DHFR (0.38) | BCHESLC6A3DHFR | |
| SCHEMBL10697204 | 0.78 | DHFR (0.41) | BCHEDHFR | |
| SCHEMBL11769466 | 0.78 | SLC6A3 (0.49) | SLC6A3DHFR | |
| SCHEMBL9119543 | 0.77 | DHFR (0.39) | BCHESLC6A3DHFR | |
| SCHEMBL10698116 | 0.76 | CYSLTR2 (0.39) | SLC6A3DHFR | |
| SCHEMBL8903203 | 0.76 | DHFR (0.42) | BCHESLC6A3DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271287-A2 | Quinoline dioic acids and amides | MERCK FROSST CANADA INC. (CA) | 1988-06-15 | — | — | EP | disclosed |