Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.79 |
| ▸ | DRD3 | P35462 | 6/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CCR1 | P32246 | 3/20 | 0.72 |
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | DRD1 | P21728 | 4/20 | 0.65 |
| ▸ | DRD5 | P21918 | 4/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.65 |
| ▸ | HRH1 | P35367 | 4/20 | 0.65 |
| ▸ | HTR2B | P41595 | 4/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904905 | 0.88 | DRD2 (0.83) | DRD2DRD3SIGMAR1LMNACCR1 | |
| Hydroxyhaloperidol SCHEMBL4540106 | 0.88 | DRD2 (1.00) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL9105624 | 0.84 | CCR1 (1.00) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL904900 | 0.82 | DRD2 (0.72) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL11792972 | 0.82 | DRD2 (0.88) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL11604166 | 0.81 | DRD2 (0.71) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL27945065 | 0.80 | DRD2 (0.66) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL4060617 | 0.79 | DRD2 (1.00) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL8010420 | 0.78 | DRD2 (0.72) | DRD2DRD3SIGMAR1LMNACCR1 | |
| SCHEMBL11932477 | 0.78 | CCR1 (0.69) | DRD2DRD3SIGMAR1LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260070-A1 | The acetic acid ester of haloperidol and pharmaceutical compositions thereof | H. LUNDBECK A/S (DK) | 1988-03-16 | — | — | EP | disclosed |