Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569447 | 0.84 | EPHX2 (0.46) | SMN1; SMN2ALDH1A1TSHRCYP3A4CHRM2 | |
| SCHEMBL5510787 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1TSHREPHX1KDM4E | |
| SCHEMBL13080892 | 0.78 | SHBG (0.41) | SMN1; SMN2ALDH1A1TSHRCYP3A4CHRM2 | |
| SCHEMBL28668295 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TSHRCHRM1ADRA1A | |
| SCHEMBL15986102 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP3A4CHRM2HTR1A | |
| SCHEMBL20377968 | 0.75 | CA12 (0.47) | SMN1; SMN2ALDH1A1CYP3A4LMNAEPHX1 | |
| SCHEMBL20377962 | 0.75 | CA12 (0.47) | SMN1; SMN2ALDH1A1CYP3A4LMNAEPHX1 | |
| SCHEMBL20377963 | 0.75 | CA12 (0.47) | SMN1; SMN2ALDH1A1CYP3A4LMNAEPHX1 | |
| SCHEMBL24219174 | 0.74 | MEN1 (0.39) | TSHRCYP1A2EPHX1SHBG | |
| SCHEMBL25764901 | 0.72 | SHBG (0.41) | SMN1; SMN2ALDH1A1SLC6A2SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273531-A1 | 1-Methyl-1h-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-07-06 | — | — | EP | disclosed |