Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519170 | 0.84 | DPP8 (0.38) | CCR5ATMTDP1ALDH1A1MAPT | |
| SCHEMBL9520260 | 0.84 | ALDH1A1 (0.36) | CCR5ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9522365 | 0.83 | ALDH1A1 (0.36) | CCR5ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10371377 | 0.82 | ALDH1A1 (0.39) | ATMTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10390470 | 0.82 | ATM (0.39) | ATMTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10370148 | 0.81 | GAA (0.38) | CCR5ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8112276 | 0.81 | CCR5 (0.39) | CCR5ATMTDP1ALDH1A1MAPT | |
| SCHEMBL9039568 | 0.81 | ATM (0.41) | CCR5ATMTDP1ALDH1A1MAPT | |
| SCHEMBL10862981 | 0.81 | ATM (0.41) | CCR5ATMTDP1ALDH1A1MAPT | |
| SCHEMBL10391485 | 0.80 | ECE1 (0.37) | CCR5ATMTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |