Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701434 | 0.81 | ALDH1A1 (0.42) | POLBPTGS1INSRIGF1RALDH1A1 | |
| SCHEMBL10700071 | 0.78 | POLB (0.37) | POLBINSRIGF1RBRD4GAA | |
| SCHEMBL10701267 | 0.75 | CACNA2D1 (0.37) | TSHRCYP2C19 | |
| SCHEMBL178994 | 0.75 | KMT2A (0.51) | PTGS1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21955913 | 0.75 | KMT2A (0.54) | POLBBRD4GAAMEN1KMT2A | |
| SCHEMBL9770262 | 0.70 | POLB (0.35) | POLBINSRIGF1RALDH1A1KDM4E | |
| SCHEMBL108170 | 0.69 | SMN1; SMN2 (0.50) | PTGS1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL178998 | 0.69 | POLB (0.46) | POLBPTGS1INSRIGF1RALDH1A1 | |
| SCHEMBL10530320 | 0.69 | PTGS1 (0.51) | PTGS1INSRIGF1RALDH1A1KDM4E | |
| SCHEMBL11862228 | 0.68 | PTGS1 (0.54) | PTGS1INSRIGF1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |