Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701267 | 0.87 | CACNA2D1 (0.37) | CCR5 | |
| SCHEMBL10700782 | 0.85 | MEN1 (0.43) | ATMKMT2AMEN1HTT | |
| SCHEMBL10401867 | 0.82 | TSHR (0.34) | POLBGAA | |
| SCHEMBL10700121 | 0.82 | BRD4 (0.36) | POLBATMKMT2ABRD4MEN1 | |
| SCHEMBL10700196 | 0.82 | TSHR (0.36) | POLBATMKMT2AMEN1GAA | |
| SCHEMBL10700025 | 0.78 | POLB (0.39) | POLBKMT2ABRD4MEN1INSR | |
| SCHEMBL8597022 | 0.77 | ATM (0.42) | POLBATMKMT2AMEN1 | |
| SCHEMBL7828421 | 0.77 | ATM (0.42) | POLBATMKMT2AMEN1 | |
| Water SCHEMBL8600954 | 0.76 | ATM (0.42) | POLBATMKMT2AMEN1 | |
| SCHEMBL10817522 | 0.75 | POLB (0.34) | POLBCCR5KMT2ABRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293532-A1 | 6- or 7-beta-[2-[4-(substituted)-2,3-dioxopiperazin-1-yl) carbonylamino]-(substituted)acetamido]-penicillin and cephalosporin derivatives | BEECHAM GROUP PLC (GB) | 1988-12-07 | — | — | EP | disclosed |