Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389638 | 0.85 | ACE (0.44) | TAAR1ACETSHRHRH1LMNA | |
| SCHEMBL28520520 | 0.83 | LMNA (0.52) | ACERAB9ALMNA | |
| SCHEMBL21473270 | 0.83 | LMNA (0.52) | ACERAB9ALMNA | |
| SCHEMBL21465109 | 0.83 | LMNA (0.52) | ACERAB9ALMNA | |
| SCHEMBL8443421 | 0.82 | HRH1 (0.46) | HTR2ATAAR1DPP4TSHRF2 | |
| SCHEMBL21473271 | 0.81 | ACE (0.45) | HTR2ATAAR1ACETSHRLMNA | |
| SCHEMBL11182324 | 0.81 | ACE (0.49) | ACELMNA | |
| SCHEMBL28890672 | 0.81 | TSHR (0.42) | HTR2ATAAR1ACEDPP4TSHR | |
| SCHEMBL647478 | 0.80 | HTR2A (0.42) | HTR2ATAAR1DPP4TSHRF2 | |
| SCHEMBL8727416 | 0.79 | HRH1 (0.39) | HTR2ATAAR1DPP4TSHRF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288202-A2 | Fluoro-sulfones | MERCK FROSST CANADA INC. (CA) | 1988-10-26 | — | — | EP | disclosed |
| EP-0244164-A1 | Stereoselective synthesis of leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1987-11-04 | — | — | EP | disclosed |