SCHEMBL28890672

SCHEMBL28890672

SC(CC(Cl)C(Cl)Cl)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
ACE P12821 1/20 0.36
HTR2A P28223 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
HRH1 P35367 2/20 0.32
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
GRM7 Q14831 1/20 0.32
DPP4 P27487 2/20 0.32
F2 P00734 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
TRPA1 O75762 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10700271 0.81 HTR2A (0.43) TSHRACEHTR2ATAAR1HRH1
SCHEMBL11389638 0.73 ACE (0.44) TSHRACETAAR1HRH1LMNA
SCHEMBL5145613 0.72 TSHR (0.43) TSHRHTR2ATAAR1HRH1MTOR
SCHEMBL21473270 0.71 LMNA (0.52) ACERAB9ALMNA
SCHEMBL28520520 0.71 LMNA (0.52) ACERAB9ALMNA
SCHEMBL21465109 0.71 LMNA (0.52) ACERAB9ALMNA
SCHEMBL8443421 0.71 HRH1 (0.46) TSHRHTR2ATAAR1HRH1MTOR
SCHEMBL21473271 0.70 ACE (0.45) TSHRACEHTR2ATAAR1LMNA
SCHEMBL11182324 0.70 ACE (0.49) ACELMNA
SCHEMBL3996913 0.69 TSHR (0.52) TSHRHTR2ATAAR1DPP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115354350-A Method for electrocatalytic in-situ nitration of halogenated aromatic hydrocarbon 平顶山学院 2022-11-18 CN disclosed