Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | RHEB | Q15382 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783527 | 0.81 | MAPK1 (0.44) | TDP1MAPK1MAPTKMT2AMEN1 | |
| SCHEMBL9359042 | 0.81 | CYP3A4 (0.43) | TDP1MAPK1MAPTKMT2AMEN1 | |
| SCHEMBL11232599 | 0.79 | PDE7A (0.44) | TDP1MAPK1MAPTKMT2AMEN1 | |
| SCHEMBL10600257 | 0.79 | MAPK1 (0.43) | TDP1MAPK1 | |
| SCHEMBL11720359 | 0.76 | AR (0.47) | TDP1MAPK1PGR | |
| SCHEMBL11603241 | 0.75 | CYP3A4 (0.42) | TDP1MAPTKMT2AMEN1POLB | |
| SCHEMBL242048 | 0.74 | LTA4H (0.50) | LTA4HTSHRCA1CA2CYP3A4 | |
| SCHEMBL62179 | 0.74 | AKR1C3 (0.46) | TDP1MAPK1MAPTKMT2AMEN1 | |
| SCHEMBL10449741 | 0.73 | TDP1 (0.52) | TDP1MAPK1KMT2AMEN1TSHR | |
| SCHEMBL10906029 | 0.72 | CYP3A4 (0.45) | TDP1MAPK1KMT2ALTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280921-A2 | [N-benzoyle-N'-(3,5-dichloro-4-phenoxy)-phenyl] ureas | BASF Aktiengesellschaft (DE) | 1988-09-07 | — | — | EP | disclosed |