Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127799 | 0.83 | CA12 (0.50) | CA12CA9PARP1ALOX15HSD17B10 | |
| SCHEMBL1567419 | 0.83 | CA12 (0.50) | CA12CA9PARP1ALOX15HSD17B10 | |
| SCHEMBL10920408 | 0.83 | CA12 (0.50) | CA12CA9PARP1ALOX15HSD17B10 | |
| SCHEMBL11742049 | 0.78 | PARP10 (0.57) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL11742053 | 0.78 | PARP10 (0.57) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL11040034 | 0.74 | CA12 (0.42) | CA12CA9PARP1ALOX15HSD17B10 | |
| SCHEMBL11216422 | 0.74 | CA12 (0.42) | CA12CA9PARP1ALOX15HSD17B10 | |
| SCHEMBL7755455 | 0.73 | CA12 (0.41) | CA12CA9PARP1HTR5AGAA | |
| SCHEMBL4073991 | 0.72 | L3MBTL1 (0.41) | CA12CA9PARP1HTR5AGAA | |
| SCHEMBL4073995 | 0.72 | L3MBTL1 (0.41) | CA12CA9PARP1HTR5AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296543-A2 | Condensation products containing nitrogen based on modified or unmodified natural resins, method of making them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-28 | — | — | EP | disclosed |
| US-4367333-A | PLASTICS | CIBA-GEIGY CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4366312-A | Metal complexes of isoindolinazines, process for their preparation and use | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |