Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160967 | 0.83 | DRD1 (0.47) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL10701614 | 0.81 | HTR2C (0.55) | DRD1DRD5 | |
| SCHEMBL11158057 | 0.80 | ADRA2A (0.41) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL10700283 | 0.80 | DRD1 (0.49) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10703949 | 0.79 | DRD1 (0.48) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11160737 | 0.76 | DRD1 (0.43) | DRD1DRD5DRD2DRD3DRD4 | |
| Fumaric Acid SCHEMBL11169294 | 0.75 | MEN1 (0.43) | DRD1DRD5DRD2DRD3DRD4 | |
| Fumaric Acid SCHEMBL11169280 | 0.75 | MEN1 (0.43) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11160741 | 0.75 | SMN1; SMN2 (0.38) | DRD1DRD5DRD2DRD3DRD4 | |
| Sulfuric Acid SCHEMBL10924229 | 0.75 | DRD1 (0.44) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |