Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | DRD5 | P21918 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10703949 | 0.99 | DRD1 (0.48) | DRD1DRD2DRD5DRD3DRD4 | |
| Sulfuric Acid SCHEMBL10924229 | 0.93 | DRD1 (0.44) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11158057 | 0.85 | ADRA2A (0.41) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL10471907 | 0.83 | DRD1 (0.44) | DRD1DRD2DRD5DRD3DRD4 | |
| Bromide SCHEMBL11159318 | 0.82 | DRD1 (0.47) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL10700526 | 0.80 | DRD1 (0.49) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11160737 | 0.79 | DRD1 (0.43) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11219447 | 0.78 | CHRNA7 (0.44) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11162519 | 0.75 | RXFP1 (0.39) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11165085 | 0.74 | DRD2 (0.43) | DRD1DRD2DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | claimed |
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |