Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935769 | 0.98 | LMNA (0.58) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL5405182 | 0.98 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL5935756 | 0.96 | LMNA (0.60) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL19830587 | 0.96 | LMNA (0.60) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL7838421 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL11492059 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL1826048 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL1859157 | 0.92 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| Piperidine SCHEMBL27279683 | 0.89 | LMNA (0.50) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL6129170 | 0.89 | POLB (0.64) | SMN1; SMN2LMNAPOLBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348455-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023033605-A1 | METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION | 주식회사 엘지화학 | 2023-03-09 | — | — | WO | disclosed |
| CN-109563085-A | piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-107531674-A | 1-heterocyclyl isochroman compounds and analogs for the treatment of CNS disorders | 赛诺维信制药公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-104341388-B | Aromatic amide derivative as well as preparation method and medicinal application thereof | 北京诺诚健华医药科技有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-101332303-A | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level | ARENA PHARM INC (US) | 2008-12-31 | — | — | CN | disclosed |
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |