Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398476 | 0.83 | GAA (0.44) | ALDH1A1RECQLGAAMAPTAPP | |
| SCHEMBL3477452 | 0.82 | GAA (0.44) | ALDH1A1GAAMAPTAPPMEN1 | |
| SCHEMBL22499933 | 0.82 | GAA (0.62) | ALDH1A1GAAMAPTTDP1MEN1 | |
| SCHEMBL7128297 | 0.81 | GAA (0.50) | ALDH1A1GAAMAPTCYP3A4MEN1 | |
| SCHEMBL11774653 | 0.81 | ALDH1A1 (0.58) | ALDH1A1RECQLGAANR1I2MAPT | |
| SCHEMBL8959076 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RECQLGAANR1I2APP | |
| SCHEMBL48239 | 0.80 | ALDH1A1 (0.75) | ALDH1A1RECQLGAANR1I2APP | |
| SCHEMBL28106819 | 0.80 | ALDH1A1 (0.75) | ALDH1A1RECQLGAANR1I2APP | |
| SCHEMBL6152657 | 0.80 | MAPT (0.50) | ALDH1A1RECQLGAAMAPT | |
| SCHEMBL11035193 | 0.78 | MAPT (0.44) | ALDH1A1RECQLGAAMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289782-A1 | Use of 2,6-dinitroanilin derivatives in hair dyeing compositions and new 2,6-dinitroanilin derivatives | Wella Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | claimed |