SCHEMBL6152657

SCHEMBL6152657

OCCNc1ccc(NCCO)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 1/20 0.44
GAA P10253 2/20 0.44
ALDH1A1 P00352 3/20 0.43
RECQL P46063 1/20 0.43
MCL1 Q07820 1/20 0.43
PRSS1 P07477 8/20 0.43
KCNH3 Q9ULD8 1/20 0.43
F2 P00734 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
TMPRSS6 Q8IU80 2/20 0.41
ST14 Q9Y5Y6 2/20 0.41
MITF O75030 1/20 0.40
LMNA P02545 1/20 0.40
TTR P02766 1/20 0.40
GLA P06280 1/20 0.40
POLB P06746 1/20 0.40
RAD52 P43351 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11507189 0.97 MAPT (0.55) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL11015521 0.92 MAPT (0.44) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL11035193 0.92 MAPT (0.44) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL271536 0.89 APP (0.50) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL295193 0.89 KCNH3 (0.54) MAPTGAAALDH1A1KCNH3LMNA
SCHEMBL3794887 0.87 ALDH1A1 (0.41) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL17323665 0.87 MAPT (0.41) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL423456 0.87 ADRA2A (0.43) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL9174960 0.87 MAPT (0.41) MAPTKDM4EMAPK1GAAALDH1A1
SCHEMBL296404 0.87 HPGD (0.46) MAPTGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
EP-2785323-B1 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW COSMETICS GMBH (AT) 2018-07-18 EP claimed
US-9125842-B2 Agent and method for coloring keratin fibers GW COSMETICS GMBH (AT) 2015-09-08 US claimed
US-20140310888-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS GW COSMETICS GMBH (AT) 2014-10-23 US claimed
WO-2012144698-A1 FOAM TYPE HAIR DYING AGENT COMPOSITION 동성제약 주식회사 (KR) 2012-10-26 WO claimed
EP-1301163-B1 OXIDATIVE HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2,4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT HENKEL KGAA (DE) 2005-01-26 EP claimed
EP-1301163-A1 OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-16 EP claimed
US-20030069149-A1 Inhibitor for inhibiting carbonaceous powder from heating up/spontaneously igniting and method of inhibiting carbonaceous powder from heating up/spontaneously igniting LION CORPORATION (JP) 2003-04-10 US claimed
WO-2002005767-A1 OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-01-24 WO claimed
WO-1995012585-A1 TEXTILE TREATMENT UNIVERSITY OF LEEDS (GB) 1995-05-11 WO claimed
US-5275853-A Moldable polymers with ether, amine or thio ether groups THE DOW CHEMICAL COMPANY (US) 1994-01-04 US claimed
EP-0479445-A2 Hydroxyl functionalized polyetheramines as barrier packaging for oxygen-sensitive materials THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP claimed
EP-0146350-A2 Hair treatment composition UNILEVER PLC (GB) 1985-06-26 EP claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP disclosed
EP-4247323-A2 GRANULATED HAIR DYE COMPOSITION Wella Germany GmbH (DE) 2023-09-27 EP disclosed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO disclosed
US-4950795-A PRINTING PLATES, PAPER COATING CIBA-GEIGY CORPORATION (US) 1990-08-21 US disclosed
EP-0146350-A2 Hair treatment composition UNILEVER PLC (GB) 1985-06-26 EP disclosed
EP-0109118-A1 Photographic colour material incorporating developing agents for colour development AGFA-GEVAERT N.V. (BE) 1984-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069149-A1 Inhibitor for inhibiting carbonaceous powder from heating up/spontaneously igniting and method of inhibiting carbonaceous powder from heating up/spontaneously igniting CBS, UPP1, NOS1 MAPT 436/4885KDM4E 3357/4885MAPK1 230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.