Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.64 |
| ▸ | PGR | P06401 | 5/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | IL6 | P05231 | 1/20 | 0.56 |
| ▸ | GLUL | P15104 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232 | 0.93 | HIF1A (0.74) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL10527431 | 0.91 | HIF1A (0.62) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL770501 | 0.91 | HIF1A (0.72) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL5087747 | 0.90 | HIF1A (0.70) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL10603555 | 0.89 | HIF1A (0.65) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL1513910 | 0.88 | HIF1A (0.61) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL1512721 | 0.88 | HIF1A (0.72) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL13270299 | 0.88 | HIF1A (0.72) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL2299293 | 0.88 | HIF1A (0.72) | HIF1APGRSERPINA6ARLMNA | |
| SCHEMBL2734212 | 0.88 | HIF1A (0.57) | HIF1APGRSERPINA6ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266719-A1 | Process for the preparation of prednisolone-17-ethyl carbonate by transposition of prednisolone-21-ethyl carbonate | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-11 | — | — | EP | disclosed |