SCHEMBL2734212

SCHEMBL2734212

CC1=CC(=O)C=C2CC[C@@H]3[C@H](C(O)C[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)COP(=O)(O)O)[C@@]12C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 13/20 0.57
▸ PGR P06401 4/20 0.57
▸ NR3C1 P04150 6/20 0.55
▸ HSD17B10 Q99714 4/20 0.55
▸ SERPINA6 P08185 3/20 0.55
▸ CYP2C19 P33261 3/20 0.55
▸ CYP3A4 P08684 3/20 0.55
▸ AR P10275 2/20 0.55
▸ NR3C2 P08235 2/20 0.55
▸ ABCB11 O95342 1/20 0.55
▸ TNF P01375 1/20 0.55
▸ IL6 P05231 1/20 0.55
▸ GLUL P15104 1/20 0.55
▸ ADAM17 P78536 1/20 0.55
▸ GPBAR1 Q8TDU6 1/20 0.55
▸ LMNA P02545 3/20 0.54
▸ CHRM1 P11229 1/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.51
▸ NFKB1 P19838 2/20 0.51
▸ MAPT P10636 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11496812 0.99 HIF1A (0.57) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL1761169 0.92 HIF1A (0.57) HIF1APGRNR3C1HSD17B10SERPINA6
Phosphoric Acid SCHEMBL5501494 0.89 NR3C1 (0.67) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL13232 0.88 HIF1A (0.74) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL10700873 0.88 HIF1A (0.64) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL2299293 0.87 HIF1A (0.72) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL1512721 0.87 HIF1A (0.72) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL13270299 0.87 HIF1A (0.72) HIF1APGRNR3C1HSD17B10SERPINA6
Phosphoric Acid SCHEMBL1929804 0.86 NR3C1 (0.64) HIF1APGRNR3C1HSD17B10SERPINA6
SCHEMBL10527431 0.86 HIF1A (0.62) HIF1APGRNR3C1HSD17B10SERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 — — US claimed
US-20210292353-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-09-23 — — US claimed
EP-3829565-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2021-06-09 — — EP claimed
WO-2020025488-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2020-02-06 — — WO claimed
CN-105997845-B A kind of application of methylprednisolone sustained-release gel and preparation method and the gel in prevention Failed Back Surgery Syndrome 西安交通大学 2019-04-09 — — CN claimed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 — — US claimed
EP-3122756-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2017-02-01 — — EP claimed
CN-105997845-A Methylprednisolone controlled-release gel, preparing method and application of gel to lumbar surgery failure syndrome prevention 西安交通大学 2016-10-12 — — CN claimed
EP-1744683-B1 APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF PARATHYROID HORMONE AGENTS ALZA CORP (US) 2016-03-16 — — EP claimed
WO-2015144282-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2015-10-01 — — WO claimed
WO-2002040029-A2 CORTICOSTEROIDS ADDUCTS WITH NATURAL POLYSACCHARIDE POLYMERS PHARMA BIOTECH LIMITED (CY) 2002-05-23 — — WO claimed
US-20240423907-A1 Improved Nasal Administration of Pharmaceutical Formulations CYRANO THERAPEUTICS, INC. 2024-12-26 — — US disclosed
CN-119012999-A Improved nasal administration of pharmaceutical formulations 思瑞诺医疗有限公司 2024-11-22 — — CN disclosed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 — — US disclosed
EP-4460284-A1 IMPROVED NASAL ADMINISTRATION OF PHARMACEUTICAL FORMULATIONS Cyrano Therapeutics, Inc. (US) 2024-11-13 — — EP disclosed
EP-1131054-A2 METHODS FOR PREPARING COATED DRUG PARTICLES AND PHARMACEUTICAL FORMULATIONS THEREOF UNIVERSITY OF FLORIDA (US) 2001-09-12 — — EP disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 — — US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 — — US disclosed
WO-2000028969-A2 METHODS FOR PREPARING COATED DRUG PARTICLES AND PHARMACEUTICAL FORMULATIONS THEREOF UNIVERSITY OF FLORIDA (US) 2000-05-25 — — WO disclosed
EP-0106115-A2 Process for the purification of alkaline salts of corticosteroid-phosphoric-acid esters and their utilization HOECHST AKTIENGESELLSCHAFT (DE) 1984-04-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 HIF1A 4074/4885PGR 1842/4885NR3C1 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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