SCHEMBL107009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14402690	1.00	ESR1 (0.61)	ESR1ESR2TAAR1SLC6A2TRPV1
	SCHEMBL10971031	0.88	ESR1 (0.53)	ESR1ESR2TAAR1SLC6A2TRPV1
	SCHEMBL14402493	0.83	ESR1 (0.43)	ESR1ESR2TAAR1SLC6A2SLC6A4
	SCHEMBL1050885	0.83	ESR1 (0.43)	ESR1ESR2TAAR1SLC6A2SLC6A4
	SCHEMBL106892	0.83	ESR1 (0.59)	ESR1ESR2TAAR1SLC6A2TRPV1
	SCHEMBL7166607	0.82	TAAR1 (0.56)	ESR1ESR2TAAR1SLC6A2TRPV1
	SCHEMBL13850021	0.82	SLC6A2 (0.48)	ESR1ESR2SLC6A2SLC6A4SLC6A3
	SCHEMBL14402398	0.82	SLC6A2 (0.48)	ESR1ESR2SLC6A2SLC6A4SLC6A3
	SCHEMBL15178192	0.82	ESR1 (0.42)	ESR1ESR2TAAR1SLC6A2SLC6A3
	SCHEMBL14402399	0.82	TRPA1 (0.48)	ESR1ESR2SLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.