Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | HTR2B | P41595 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 4/20 | 0.41 |
| ▸ | DRD5 | P21918 | 4/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709628 | 0.83 | DRD1 (0.54) | DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL10350543 | 0.78 | HTR2C (0.54) | HTR2CHTR2BHTR2A | |
| SCHEMBL10703630 | 0.74 | ESR1 (0.48) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10351352 | 0.73 | HTR2C (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL3162737 | 0.73 | HTR2A (0.74) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL4247274 | 0.71 | HTR2A (0.71) | HTR2CHTR2BHTR2A | |
| SCHEMBL6915522 | 0.70 | CA1 (0.46) | KMT2AHTR6 | |
| SCHEMBL440865 | 0.69 | CA12 (0.33) | — | |
| SCHEMBL11582017 | 0.69 | MAOB (0.46) | MEN1KMT2A | |
| SCHEMBL11743909 | 0.69 | MAOB (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |