Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743909 | 0.87 | MAOB (0.42) | MAOBESR1ESR2MAPTCA1 | |
| SCHEMBL11580901 | 0.84 | MAOB (0.43) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL3192396 | 0.83 | MAOB (0.48) | MAOBESR1ESR2MAPTCA1 | |
| SCHEMBL11584209 | 0.83 | LMNA (0.43) | MAOBESR1ESR2MAPTTP53 | |
| SCHEMBL440865 | 0.81 | CA12 (0.33) | CA1CA2TUBB1 | |
| SCHEMBL6915522 | 0.79 | CA1 (0.46) | MAPTCA1CA2TP53TSHR | |
| SCHEMBL11765918 | 0.79 | ALOX5 (0.45) | ESR1ESR2MAPTCA1CA2 | |
| SCHEMBL23554329 | 0.78 | MAOB (0.53) | MAOBESR1ESR2MAPTTP53 | |
| SCHEMBL11747368 | 0.74 | MEN1 (0.39) | ESR1ESR2MAPTTP53TSHR | |
| SCHEMBL3202166 | 0.73 | MAOB (0.44) | MAOBESR1ESR2MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066619-A | STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1978-01-03 | — | — | US | claimed |