Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 6/20 | 0.54 |
| ▸ | DRD5 | P21918 | 6/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701316 | 0.83 | HTR2C (0.48) | DRD1DRD5 | |
| SCHEMBL10700207 | 0.81 | DRD1 (0.51) | DRD1DRD5DRD4DRD2DRD3 | |
| SCHEMBL10703630 | 0.81 | ESR1 (0.48) | KDM4EALOX15HSD17B10 | |
| SCHEMBL11158095 | 0.78 | DRD1 (0.45) | DRD1DRD5DRD4DRD2DRD3 | |
| SCHEMBL11169272 | 0.73 | MAOA (0.84) | DRD1DRD5DRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11158000 | 0.71 | MAOA (0.81) | DRD1DRD5DRD4DRD2DRD3 | |
| SCHEMBL6915522 | 0.70 | CA1 (0.46) | CYP3A4KDM4EALOX15HSD17B10 | |
| SCHEMBL10747934 | 0.70 | CYP2D6 (0.74) | DRD1DRD5DRD2SLC6A4CYP3A4 | |
| SCHEMBL11582017 | 0.69 | MAOB (0.46) | MAOBCYP3A4KDM4EHSD17B10 | |
| SCHEMBL440865 | 0.69 | CA12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285287-A2 | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1988-10-05 | — | — | EP | disclosed |