Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742301 | 0.80 | TRPA1 (0.50) | TRPA1KMT2AMEN1GPR84ALDH1A1 | |
| SCHEMBL3261185 | 0.75 | — | — | |
| SCHEMBL6208056 | 0.71 | TRPA1 (0.58) | TRPA1KMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL11555963 | 0.68 | TRPA1 (0.41) | TRPA1KMT2AMEN1GPR84ALOX15 | |
| Acetic Acid SCHEMBL11657200 | 0.67 | NOX1 (0.47) | TRPA1KMT2AMEN1GPR84ALOX15 | |
| SCHEMBL24592151 | 0.67 | CYP11B2 (0.40) | CA12CA1CA2CA9KDM1A | |
| SCHEMBL401773 | 0.67 | TRPA1 (0.40) | TRPA1CA12CA1CA2CA9 | |
| SCHEMBL5094762 | 0.67 | MAPT (0.61) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10698743 | 0.67 | MEN1 (0.46) | TRPA1CA12CA1CA2CA9 | |
| SCHEMBL14080070 | 0.66 | TRPA1 (0.38) | TRPA1KMT2AMEN1GPR84ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270692-A1 | ANTIARRHYTHMIC AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-06-15 | — | — | EP | disclosed |