Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704935 | 0.89 | TRPA1 (0.46) | TRPA1CYP1A2MEN1KMT2AMCHR1 | |
| SCHEMBL10707204 | 0.89 | HDAC6 (0.47) | HDAC6TRPA1MEN1KMT2ANPC1 | |
| SCHEMBL10706436 | 0.88 | HDAC6 (0.46) | HDAC6MEN1KMT2AMCHR1EPHX2 | |
| SCHEMBL10704963 | 0.86 | HDAC6 (0.42) | HDAC6TRPA1CYP1A2MEN1KMT2A | |
| SCHEMBL10703872 | 0.85 | HDAC6 (0.43) | HDAC6MEN1KMT2AMCHR1EPHX2 | |
| SCHEMBL10714679 | 0.85 | HDAC6 (0.43) | HDAC6MEN1KMT2AMCHR1EPHX2 | |
| SCHEMBL10704429 | 0.84 | MAPT (0.41) | HDAC6TRPA1MEN1KMT2ANPC1 | |
| SCHEMBL10705572 | 0.83 | TDP1 (0.50) | HDAC6MEN1KMT2AMCHR1MLYCD | |
| SCHEMBL10703856 | 0.82 | NPC1 (0.43) | MEN1KMT2AMCHR1EPHX2NPC1 | |
| Penfluron SCHEMBL117735 | 0.81 | EPHX2 (0.60) | TRPA1CYP1A2MEN1KMT2AIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |
| EP-0116729-A2 | Benzoylurea compounds and pesticidal compositions comprisingsame | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-08-29 | — | — | EP | disclosed |