Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705614 | 0.90 | TDP1 (0.53) | TDP1LMNARORCNPSR1PCTP | |
| SCHEMBL10714234 | 0.89 | LMNA (0.52) | TDP1LMNAHDAC6PCTPMEN1 | |
| SCHEMBL10705199 | 0.89 | LMNA (0.51) | TDP1LMNAHDAC6PCTPMEN1 | |
| SCHEMBL10714350 | 0.87 | TDP1 (0.58) | TDP1LMNARORCHDAC6PCTP | |
| SCHEMBL10706279 | 0.87 | GCGR (0.50) | TDP1LMNAHDAC6PCTPMEN1 | |
| SCHEMBL10705504 | 0.86 | GCGR (0.49) | TDP1LMNAHDAC6PCTPMEN1 | |
| SCHEMBL10704423 | 0.84 | TDP1 (0.49) | TDP1LMNARORCPCTPMEN1 | |
| SCHEMBL10705546 | 0.83 | GCGR (0.53) | TDP1LMNAPCTPMEN1KMT2A | |
| SCHEMBL10703203 | 0.83 | HDAC6 (0.47) | NPSR1HDAC6MEN1KMT2AGAA | |
| Chlotrifmeuron SCHEMBL10868747 | 0.82 | TDP1 (0.70) | TDP1LMNARORCPCTPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |