SCHEMBL10703259

SCHEMBL10703259

CC1(CN(CC2(C)CO2)C(=O)CCCC(=O)N(CC2(C)CO2)CC2(C)CO2)CO1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10707697 0.96 LMNA (0.40) LMNAALDH1A1
SCHEMBL10704596 0.94 LMNA (0.39) LMNAALDH1A1
SCHEMBL10703213 0.94 LMNA (0.39) LMNAALDH1A1
SCHEMBL11159993 0.94 LMNA (0.39) LMNAALDH1A1
SCHEMBL10704401 0.94 LMNA (0.39) LMNAALDH1A1
SCHEMBL10702783 0.92 LMNA (0.33) LMNA
SCHEMBL11170499 0.90 LMNA (0.37) LMNAALDH1A1
SCHEMBL11171758 0.86 LMNA (0.34) LMNAALDH1A1
SCHEMBL10706333 0.83
SCHEMBL11165362 0.82 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0094436-B1 N-GLYCIDYL-SUBSTITUTED AMIDE COMPOUNDS MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-30 EP disclosed
EP-0094436-A1 N-GLYCIDYL-SUBSTITUTED AMIDE COMPOUNDS MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-11-23 EP disclosed