SCHEMBL1070427

SCHEMBL1070427

OCCCCCCCCCCCc1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.65
ADRA2A P08913 3/20 0.65
SLC6A2 P23975 3/20 0.65
ADORA3 P0DMS8 2/20 0.65
TACR2 P21452 2/20 0.65
SLC6A4 P31645 2/20 0.65
SLC6A3 Q01959 2/20 0.65
KDM4E B2RXH2 2/20 0.65
ALDH1A1 P00352 2/20 0.65
ACHE P22303 2/20 0.65
LMNA P02545 1/20 0.65
SHBG P04278 1/20 0.65
TP53 P04637 1/20 0.65
CYP3A4 P08684 1/20 0.65
HSPD1 P10809 1/20 0.65
ADRB3 P13945 1/20 0.65
HTR2C P28335 1/20 0.65
HSPE1 P61604 1/20 0.65
HIF1A Q16665 1/20 0.65
TST Q16762 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10405809 1.00 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL7368216 1.00 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL8055358 1.00 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL26331386 1.00 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL11228648 1.00 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL1172078 0.98 CA2 (0.68) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL274830 0.90 CA2 (0.71) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL23837668 0.90 CA2 (0.63) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL9165397 0.90 ESR1 (0.77) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL7784766 0.90 ESR1 (0.77) ESR1ADRA2ASLC6A2ADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2159611-B1 Polymerizable liquid crystal and oriented polymer film SUMITOMO CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-8518299-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2013-08-27 US disclosed
US-8518299-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2013-08-27 US disclosed
US-8518299-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2013-08-27 US disclosed
EP-1682930-B1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM SUMITOMO CHEMICAL CO (JP) 2011-01-19 EP disclosed
EP-1682930-B1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM SUMITOMO CHEMICAL CO (JP) 2011-01-19 EP disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM LUB JOHAN 2010-10-21 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
US-7763330-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2010-07-27 US disclosed
EP-2159611-A1 Polymerizable liquid crystal and oriented polymer film Sumitomo Chemical Company, Limited (JP) 2010-03-03 EP disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
US-20070024970-A1 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2007-02-01 US disclosed
EP-1682930-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM Koninklijke Philips Electronics N.V. (NL) 2006-07-26 EP disclosed
WO-2005045485-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267858-A1 DICHROIC GUEST-HOST POLARIZER COMPRISING AN ORIENTED POLYMER FILM ZW10, DSC1, VIM ESR1 4644/4885ADRA2A 3487/4885SLC6A2 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.