Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704379 | 1.00 | CPA1 (0.36) | CPA1PLA2G10ALDH1A1MEN1LMNA | |
| SCHEMBL10704375 | 1.00 | CPA1 (0.36) | CPA1PLA2G10ALDH1A1MEN1LMNA | |
| SCHEMBL25291547 | 0.75 | ALDH1A1 (0.42) | PLA2G10ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL27651567 | 0.75 | ALDH1A1 (0.42) | PLA2G10ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3306198 | 0.75 | ALDH1A1 (0.42) | PLA2G10ALDH1A1MEN1LMNAKMT2A | |
| Benzene SCHEMBL28850626 | 0.72 | CNR1 (0.43) | ALDH1A1MEN1LMNAKMT2AMAPK1 | |
| SCHEMBL26965341 | 0.72 | PLA2G10 (0.42) | PLA2G10ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL27120254 | 0.72 | PLA2G10 (0.42) | PLA2G10ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4436363 | 0.71 | CPA1 (0.38) | CPA1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4436371 | 0.71 | CPA1 (0.38) | CPA1ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749781-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0223437-A2 | Aminocarbonyl renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-05-27 | — | — | EP | disclosed |