SCHEMBL1070441

SCHEMBL1070441

CCCCCCNC(CC)C(=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 10/20 0.44
NOD1 Q9Y239 1/20 0.43
CASP2 P42575 1/20 0.40
HAO1 Q9UJM8 1/20 0.39
ALOX15 P16050 1/20 0.38
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
NAAA Q02083 1/20 0.38
GPR84 Q9NQS5 2/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
TLR2 O60603 1/20 0.38
HDAC11 Q96DB2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19750215 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL7081523 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL11423050 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL25305503 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL25849737 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL25244993 0.85 NOD1 (0.51) EPHX1NOD1CASP2FNTAFNTB
SCHEMBL5309803 0.82 NOD1 (0.49) EPHX1NOD1FNTAFNTBGPR84
SCHEMBL28722621 0.78 ZDHHC7 (0.49) EPHX1NOD1CASP2
SCHEMBL14367745 0.77 CA1 (0.44) EPHX1NOD1CASP2ALOX15
SCHEMBL7342396 0.77 CA1 (0.44) EPHX1NOD1CASP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180104185-A1 LIQUID COMPOSITIONS CAPABLE OF FOAMING AND INCLUDING ACTIVE AGENTS, AND METHODS FOR MAKING OR DEVELOPING SAME MIKA PHARMA GMBH 2018-04-19 US disclosed
US-9693956-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH 2017-07-04 US disclosed
EP-2387391-B1 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GES FÜR DIE ENTW UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2017-01-11 EP disclosed
US-20160022579-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH 2016-01-28 US disclosed
US-9005626-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH (DE) 2015-04-14 US disclosed
EP-2387391-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2011-11-23 EP disclosed
US-20110269704-A1 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FUR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-11-03 US disclosed
WO-2011009436-A9 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-03-31 WO disclosed
US-20110059117-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH (DE) 2011-03-10 US disclosed
WO-2011009436-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-01-27 WO disclosed