SCHEMBL10704669

SCHEMBL10704669

CCCN(C=CC=C(C#N)C#N)CCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33
TNNC1 P63316 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11336810 0.89 MEN1 (0.33) APPMEN1USP2ALDH1A1MAPT
SCHEMBL6542381 0.85 MEN1 (0.37) APPMEN1USP2ALDH1A1MAPT
SCHEMBL8504335 0.85 MEN1 (0.34) APPMEN1USP2ALDH1A1MAPT
SCHEMBL14330128 0.85 MEN1 (0.37) APPMEN1USP2ALDH1A1MAPT
SCHEMBL801343 0.85 MEN1 (0.37) APPMEN1USP2ALDH1A1MAPT
SCHEMBL12758231 0.83 APP (0.35) APPMEN1USP2ALDH1A1MAPT
SCHEMBL11492951 0.80 APP (0.30) APP
SCHEMBL11333333 0.79 ZDHHC20 (0.35) MEN1USP2ALDH1A1MAPTKMT2A
SCHEMBL9892457 0.75 APP (0.32) APP
SCHEMBL9889199 0.73 APP (0.32) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127819-B1 ULTRAVIOLET ABSORBER AND PHOTOGRAPHIC MATERIAL INCLUDING IT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-30 EP disclosed
US-4576908-A 3-DIALLYLAMINOALLYLIDENEMALONITRILE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-03-18 US disclosed
EP-0127819-A2 Ultraviolet absorber and photographic material including it MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-12-12 EP disclosed