SCHEMBL11333333

SCHEMBL11333333

CCCCN(C=CC=C(C#N)C#N)CC#N

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11336810 0.90 MEN1 (0.33) MEN1KMT2AUSP2ALDH1A1POLB
SCHEMBL8504335 0.87 MEN1 (0.34) ZDHHC20ZDHHC2MEN1KMT2AUSP2
SCHEMBL801343 0.83 MEN1 (0.37) ZDHHC20ZDHHC2MEN1KMT2AUSP2
SCHEMBL6542381 0.83 MEN1 (0.37) ZDHHC20ZDHHC2MEN1KMT2AUSP2
SCHEMBL14330128 0.83 MEN1 (0.37) ZDHHC20ZDHHC2MEN1KMT2AUSP2
SCHEMBL9892457 0.82 APP (0.32)
SCHEMBL10704669 0.79 APP (0.33) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL14330080 0.76 ALDH1A1 (0.40) ALDH1A1
SCHEMBL12758231 0.75 APP (0.35) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12864668 0.72 DNM1 (0.36) ZDHHC20ZDHHC2MEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed