SCHEMBL10705000

SCHEMBL10705000

CCN(CC)S(=O)(=O)N(SC(F)(Cl)Cl)c1ccc(Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
CNR2 P34972 8/20 0.36
CNR1 P21554 6/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 3/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10865541 0.90 CDK1 (0.40) CNR2CNR1ALDH1A1MAPTMEN1
SCHEMBL10708468 0.88 TSHR (0.36) TSHRCNR2CNR1ALDH1A1HSD17B10
SCHEMBL11315236 0.76 ALDH1A1 (0.37) TSHRCNR2ALDH1A1HSD17B10MAPT
SCHEMBL11370118 0.73 ALDH1A1 (0.38) TSHRKDM4EALDH1A1HPGDALOX15
SCHEMBL30606188 0.73 KDM4E (0.35) TSHRCNR2CNR1KDM4EALDH1A1
Tolylfluanid SCHEMBL21309 0.73 CDK1 (0.42) TSHRKDM4EALDH1A1HPGDMAPT
Dichlofluanid SCHEMBL20684 0.71 POLB (0.38) TSHRKDM4EALDH1A1MAPTTDP1
Dichlofluanid SCHEMBL13858863 0.71 POLB (0.38) TSHRKDM4EALDH1A1MAPTTDP1
SCHEMBL11390996 0.70 RAB9A (0.41) KDM4EALDH1A1MAPTMEN1GAA
SCHEMBL11369479 0.70 ALDH1A1 (0.37) KDM4EALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170168-B1 N,N,-DIETHYL, N'-ARYL, N'-(DICHLORFLUORMETHYLTHIO)SULFAMIDE-MICROBIOCIDES BAYER AG (DE) 1988-04-20 EP disclosed
EP-0170168-A2 N,N,-diethyl, N'-aryl, N'-(dichlorfluormethylthio)sulfamide-microbiocides BAYER AG (DE) 1986-02-05 EP disclosed