SCHEMBL10705355

SCHEMBL10705355

C=CC=CC(=O)c1ccco1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
MAOB P27338 5/20 0.61
NPC1 O15118 3/20 0.61
MAOA P21397 2/20 0.61
ALDH1A1 P00352 2/20 0.61
POLB P06746 1/20 0.61
RAB9A P51151 4/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 1/20 0.53
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
GPR52 Q9Y2T5 1/20 0.53
PSMD14 O00487 1/20 0.53
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6993038 0.84 MAPT (0.62) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL6993037 0.84 MAPT (0.62) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL8752642 0.83 MAPT (0.63) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL2134381 0.80
SCHEMBL11606021 0.79 MAPT (0.57) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL10352735 0.77 MAPT (0.56) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL11331924 0.77 MAPT (0.60) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL10352737 0.77 MAPT (0.56) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL10523362 0.77 MAPT (0.60) MAPTMAOBNPC1MAOAALDH1A1
SCHEMBL14044964 0.74 HCAR2 (0.65) MAPTMAOBNPC1MAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107761374-A A kind of antibacterial, the fabric/fiber dressing liquid of insecticidal medium and its application method and textile article/fibre/paper products 牛绍英 2018-03-06 CN disclosed
EP-0119831-B1 HEAT BLEACHABLE DYE SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-01-07 EP disclosed
US-4594312-A Photothermographic medium MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-06-10 US disclosed
EP-0119831-A2 Heat bleachable dye systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-09-26 EP disclosed