Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978637 | 1.00 | HCAR2 (0.65) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL6993037 | 0.84 | MAPT (0.62) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6993038 | 0.84 | MAPT (0.62) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL11701729 | 0.83 | MAPT (0.87) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL11701738 | 0.83 | MAPT (0.87) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28286931 | 0.81 | CES2 (0.54) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL979497 | 0.80 | HCAR2 (0.74) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL979495 | 0.80 | HCAR2 (0.74) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL7142763 | 0.80 | HCAR2 (0.74) | HCAR2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8290646 | 0.80 | MAPT (0.76) | HCAR2MAPTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290427-B2 | Anti-invasive compounds | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | claimed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | claimed |
| EP-2810198-A1 | ANTI-INVASIVE COMPOUNDS | Universiteit Gent (BE) | 2014-12-10 | — | — | EP | claimed |
| WO-2013113722-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-08-08 | — | — | WO | claimed |
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-9290427-B2 | Anti-invasive compounds | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| EP-2810198-A1 | ANTI-INVASIVE COMPOUNDS | Universiteit Gent (BE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013113722-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-08-08 | — | — | WO | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | HCAR2 672/4885MAPT 2150/4885KMT2A 1738/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | HCAR2 672/4885MAPT 2150/4885KMT2A 1738/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | HCAR2 672/4885MAPT 2150/4885KMT2A 1738/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | HCAR2 672/4885MAPT 2150/4885KMT2A 1738/4885 |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | MMP3, MMP10, MIF | HCAR2 2051/4885MAPT 3571/4885KMT2A 4319/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | HCAR2 672/4885MAPT 2150/4885KMT2A 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.