Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FABP2 | P12104 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27850093 | 0.98 | MAOB (0.52) | MAOBNPSR1GRIA4PTGS1PGR | |
| SCHEMBL6188617 | 0.85 | GRIA4 (0.50) | MAOBNPSR1GRIA4PTGS1PGR | |
| SCHEMBL29867575 | 0.83 | AKR1C3 (0.69) | NPSR1PTGS1MEN1KMT2AMAPT | |
| SCHEMBL1072964 | 0.83 | AKR1C3 (0.69) | NPSR1PTGS1MEN1KMT2AMAPT | |
| SCHEMBL11851177 | 0.83 | AKR1C3 (0.69) | NPSR1PTGS1MEN1KMT2AMAPT | |
| SCHEMBL8755498 | 0.82 | LMNA (0.74) | MAOBNPSR1PTGS1PGRPDE4A | |
| SCHEMBL4217335 | 0.82 | LMNA (0.74) | MAOBNPSR1PTGS1PGRPDE4A | |
| SCHEMBL1543413 | 0.82 | LMNA (0.74) | MAOBNPSR1PTGS1PGRPDE4A | |
| SCHEMBL8755011 | 0.82 | LMNA (0.74) | MAOBNPSR1PTGS1PGRPDE4A | |
| SCHEMBL8755392 | 0.82 | LMNA (0.74) | MAOBNPSR1PTGS1PGRPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100120-B1 | IMPROVEMENT IN THE PROCESS FOR PREPARING BIARYL COMPOUNDS VIA COUPLING OF AN ARYLAMINE WITH AN ARENE | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |
| US-4542233-A | Process for preparing biaryl compounds via coupling of an arylamine with an arene | BIASCHIM S.P.A. (IT) | 1985-09-17 | — | — | US | disclosed |
| EP-0100120-A1 | Improvement in the process for preparing biaryl compounds via coupling of an arylamine with an arene | Nobel Chemicals AB (SE) | 1984-02-08 | — | — | EP | disclosed |